In vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni was .. and characterization of polyphenol oxidase from leaves of Cleome gynandra L. Food . Protective effect of standardized extract of Cleome viscosa against Animals; Anti-Ulcer Agents/administration & dosage; Anti-Ulcer. Research Journal of Pharmacognosy and Phytochemistry. Delivering full text access to the world’s highest quality literature.

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Estimation of total phenolic content The total phenolic content in B. J Pharm Sci Res. Kumar A, Chattopadhyay S. The percentage of scavenging activity was derived using the following formula. The gastric tissue samples were fixed in neutral buffered formalin for 24 h.

RJPP – Anti-ulcer activity of Cleome viscose linn. against gastric ulcer in rats

From the incubated mixture, 0. Extract obtained by Soxhlation showed higher total phenolic and flavonoid contents. The results of this investigation showcase the potential antiulcer and antioxidant activities of ethanol EBG. From the present study results reveals the antiulcer activity of ethanol extract leaves which is comparable to that of Omeprazole.

One hundred grams powdered leaves was antiulver after defatted with petroleum ether and successively extracted with ethanol using Soxhlet apparatus subsequently NO is a potent pleiotropic mediator of physiological processes such as neuronal signaling, smooth muscle relaxant, regulation of cell-mediated toxicity, and inhibition of platelet aggregation. The half maximal inhibitory concentration, m: Eur J Clin Invest.


Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in rats. Phytochemical screening was carried out to identify the secondary metabolites present in defatted ethanol EBG. The roots are a remedy for scurvy and rheumatism. The experiment was done in triplicate.

Antiulcer Herbs

The animals were housed in colony cages and maintained under standard environmental conditions: He has published and presented papers in reputed National and International journals and conferences. Abstract Cleome viscosa linn. An aqueous seed extract displayed significant analgesic activity in mice and local anaesthetic activity in guinea pigs. In tests with rats the anti-diarrhoeal and antipyretic. Capparidaceae is also known as Tickweed, or Spider plant.

Evaluation of antiucler potential of selected mangrove plants. Financial support and sponsorship Nil.

Amelioration of chronic ileitis by nitric oxide synthase inhibition. The ethanolic EBG leaves revealed the presence of alkaloids, saponins, terpenoids, flavonoids, steroids, cardiac glycosides, tannins, aminoacids, and proteins [ Table 1 ].

Purification and characterization of polyphenol oxidase from leaves of Cleome gynandra L. The whole herb is used in treatment of inflammation of the middle ear and applied on wounds and ulcers, so the research was to prove experimentally anti ulcer activity in whole plant of Cleome viscosa linn.

Peptic ulcer is a digestive disorder most commonly found in clinical practice. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, pH, free acidity, total acidity and ulcer index. The ethanol extracts showed good antioxidant capacity in DPPH radical scavenging assay and NO radical scavenging activity when compared to standard.


The current treatment of peptic ulcer is mainly done with H 2 receptor antagonists, proton pump inhibitors, and antimuscarinics. Ligation was done without causing any damage to the blood supply of the stomach. In vitro anti-inflammatory, anticancer and antioxidant activities.

The photometric evaluation of the antioxidant capacity of the ethanolic EBG leaves showed good antioxidant capacity [ Figure 3 ]. He is life member of APTI. This is the first ever report of antiulcer and antioxidant activities in B. However, most of these treatments produce adverse reaction such as hypersensitivity, arrhythmia, impotence, gynecomastia, and hematopoietic disorders.

Antiulcer Herbs

J Pharmacol Exp Ther. An aqueous seed extract displayed significant analgesic activity in mice and local anaesthetic activity in guinea pigs. Many medicinal plants contain higher phenolic compounds antiulcdr as flavonoids, monophenols, and polyphenols. Animal selection The experiments were carried out on Wistar strain male adult rats, aged 12—15 weeks and weighing — m. It is a diffusible free radical which plays many roles as an effectors molecule in diverse biological systems including vasodilatation, antimicrobial, neuronal messenger, and antitumor activities.