Atelektazili yenidoğan bebeklerde nebülize rhDNaz tedavisi Gereç ve yöntem: Akciğerlerinde atelektazi olan 8 yenidoğan (7 prematüre) retrospektif olarak. darlığın tanı, tedavisi ve koruyucu hekimlikte yapılması gerekenler tartışıldı. ABSTRACT . atelektazi, yutma zorluğu, üst gastrointestinal kanamalar ve ölümdür. Tanı ve tedavisinde konsensüs olmamasına karşın günümüzde tedavisi sıklıkla rekürrent pnömoni, atelektazi; üriner sistem tutulumlarında obstrüksiyon.

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Clinical and radiological responses were evaluated separately. The age distribution of the cases was between 7 and 56 years, and the mean age was Chest physiotherapy and tracheal aspiration was performed 1 hour after the second dose.

Türkiye Klinikleri Tıp Bilimleri Dergisi

Behcet Uz Children’s Hospital. Twelve intubated patients received 1. In our study, of the pulmonary hydatid cyst cases operated on between and atellektazi, 76 cases had ruptured into the pleura for various reasons, and the different clinicoradiological presentations were evaluated retrospectively. Morbidity was observed in 30 cases Spontaneous perforation was detected in the other 60 The most frequent symptom due to pleural rupture in patients was dyspnea 44 cases, An anthelmintic drug use history atelektaxi found in three cases of ruptured pleura.



Two cases that were admitted to the emergency unit and were immediately administered a tube thoracostomy developed tension pneumothorax. The mean duration of hospitalization was determined to be Possible parenchymal protection should be applied atwlektazi surgical treatment, and anatomic resection should not be performed unless necessary.

Atelectasis was the most frequent cause of morbidity in these patients 10 cases. Atelectasis increases the risk of secondary pulmonary infections related with prolonged artificial ventilation.

Therefore, it requires early and aggressive treatment in newborns cared in neonatal intensive care units NICUs. The same protocol was repeated on the second day.

Nebulized route was more successful than the intratracheal route.

Response to rhDNase was better in cases with upper lung lobe involvement. However, there is still no evidence-based, ”gold standard” treatment.


This disease can progress asymptomatically for a long time and can sometimes lead to life-threatening emergency situations, such as tension pneumothorax. The delayed admission of a patient to a physician causes the disease to become more complicated and to increase the morbidity and mortality rates.

Both nebulized and intratracheal rhDNase administrations are successful without any adverse reactions for the treatment of persistent atelectasis, especially in neonates with viscous secretions and pneumonia with upper lobe atelectasis. Etiologically, iatrogenic perforation was detected in four cases and thoracic trauma in nine cases six car accidents and three falls from a height.


Surgical treatment of pulmonary hydatid cysts, which perforated to the pleura.

Treatment of the disease is in the form of surgery. Hydatid cyst disease, endemic in Eastern region of Turkey, is a significant parasitic public health problem. Positive radiological and clinical responses to rhDNase and recurrence of atelectasis in the whole study group were A second dose was administered 4 hours after the atelektazii dose.

In this study, pleural complications of hydatid cysts were presented in 76 cases.

In addition, 21 cases had hydropneumothorax, 17 had pneumothorax, and 36 had pleurisy. Current treatment of atelectasis consists of certain conventional modalities. In this study, we aimed to compare and evaluate the clinical and radiological changes in infants who received nebulized ztelektazi intratracheal rhDNase for persistent atelectasis unresponsive to conventional treatment options.