Eccrine hidradenoma is a rare benign cutaneous neoplasm, believed to arise from the distal excretory duct of the eccrine sweat glands [1]. Because a. Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. Another name for tumors that were previously believed to strictly derive from specific sweat gland types may, in fact, derive from both eccrine or apocrine glands. Hidradenoma is a cutaneous, often benign tumour of the sweat glands. Also known by various other names such as nodular hidradenoma, eccrine acrospiroma.

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Sweat gland lesions originate from sweat gland or sweat duct cell lines.


Find articles by Euna Hwang. Apocrine adenocarcinoma may develop within recognisable benign tumours allowing classification as follows. Because they are deep hidradenom the skin, it is difficult to remove syringomas without causing scarring.

The incision site was closed primarily. The patient showed symptoms and signs of facial nerve paralysis on the right hemiface. Related articles Cutaneous adnexal tumor malignant nodular hidradenoma scalp tumor skull tumor.

The main specimen from the preauricular area consisted of a nodular, rubbery, firm myxoid mass, measuring 8. Discussion of sweat gland tumors can be difficult and confusing due to the complex classification and redundant terminology used to describe the same tumors.

Pathology Outlines – Hidradenoma / eccrine acrospiroma

Spiradenomas are harmless, but may be treated with conservative excision. The glands within a sweat gland naevus are increased in size and number from birth. However, a case of a benign giant eccrine hidradenoma infiltrating the deeper structures beyond the muscle layer to the cranial base has not been edcrine thus far. For example, acrospiroma and hidradenoma are synonymous, and sometimes the term acrospiroma is used to generally describe hidrasenoma sweat gland tumors.


Variants of these lesions were previously called papillary adenoma or tubulopapillary carcinoma. Views Read Edit View history.

Syringomas are benign adnexal growths with ductal syringeal differentiation, from either eccrine or apocrine lineage. Histochemistry shows positive carcinoembryonic antigen CEA immunostaining. A 41 year old man presented with history of a painless swelling over the lower right anterior abdominal wall of 8 years duration. Nodular hidradenoma of male breast: Complete surgical excision is curative. Herein, we report a case of a benign giant nodular eccrine hidradenoma in the preauricular area that had infiltrated deep structures and extended into the cranial base.

Eccriine tumor had slowly grown again over the last couple of years. Most cells were large and hidravenoma with a clear cytoplasm black arrowowing to the glycogen content. J Cutan Pathol ; They may present as papules bumpsplaques thickened patches like seborrhoeic keratosesor nodules lumps. Clear cell nodular hidradenoma involving the lymphatic system: It usually presents as a superficial dermal lesion and hence it is diagnosed early and often excised without much investigation.

Papillary adenocarcinoma is aggressive and may erode underlying bone, or metastasize to other sites of the body. Support Center Support Center. In this case, the patient presented with a unilateral paralysis of the facial nerve. We chose a simple method for the reconstructive method of the facial paralysis, considering the patient’s old age. Solid areas were grey white. It usually presents as a single, small skin-colored lesion, and is considered distinct from the closely related poroma.

By using this site, you agree to the Terms of Use and Privacy Policy. A differential diagnosis of soft tissue sarcoma like dermatofibrosarcoma protuberans was considered so was hidradenoma. Further, there was a lack of circumscription, deep extension, infiltrating growth pattern, perineural invasion, and regional metastasis of the tumor mass.

Hence all efforts must be made to obtain pre-operative histopathological diagnosis. On examination a deeply pigmented pedunculated ulcero-proliferative lesion was noted on the right lower anterior abdominal wall measuring 7. Malignant transformation has been described and there is a report of metastasis in the skeleton from a lesion in the foot [ uidradenoma – 5 ]. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Eccine for more related articles at Journal of Patient Care View PDF Download PDF.


They may also appear darker than surrounding skin. This article has been cited by other articles in PMC.

Malignant eccrine hidradenoma.

The patient continues to be closely observed for any evidence of regrowth from the remaining tumor mass. There are two types of sweat glands: Find articles by Chung Hun Kim. Hidradenomas are eccrinr definition benign, with malignant transformation very rare.

A frozen histologic examination showed no evidence of malignancy. Ann Jose ankara escort.

Eccrine glands play an important role in the regulation of body temperature. The tumor mass compressed the internal jugular vein, displaced the external carotid artery inferiorly, and extended to the cranial base around the right foramen ovale without intracranial extension Fig. On Histopathological examination both solid and cystic components are present with characteristic clear cells, which contain a large amount of glycogen and thus appear clear under light microscopy.

A review of previous reports indicated that giant eccrine hidradenoma extends from the main lesion and commonly reaches the subcutaneous tissue; however, the lesion seldom invades deep structures beyond the deep fascia.

Am J Clin Pathol ; Suppl 1: