Common Name: West African Rubber Tree. Funtumia elastica. Drawing of the leaves and flowers. Photograph by: Matilda Smith Public domain. Funtumia elastica (Preuss) Stapf [family APOCYNACEAE]. Common names. English West African rubber tree; Lagos silk rubber tree; bush rubber (Ghana. Description. Tree to 30 m tall; bole straight and cylindrical, crown narrow; bark brown to dark, thin, slightly fissured, becoming granular on old trees; Slash orange.

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Funtumia elastica

West Indian Med J. Despite this exposure, therapeutic addition of Yam-I induced rapid and robust beneficial cellular responses at the intestinal surface resulting in decreased CFU counts in feces.

Human gamma delta T cells recognize alkylamines derived from microbes, edible plants, and tea: The supernatant fluid was then filtered through a 0. Supplementary Material 01 Click here to view.

Discussion Both prophylactic and post-exposure strategies involving innate immune funtkmia by adjuvants have been shown to prevent or ameliorate infections [ 4445 ]. Bioorg Med Chem Lett. Open in a separate window. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Am J Respir Cell Mol.

Antifungal property and phytochemical screening of the crude extracts of Funtumia elastica and Mallotus oppositifolius. Cells were plated 2. Very low concentrations of Yam-I drove neutrophil recruitment peritonitis in mice that was partially tolllike receptor 4 TLR4 – and myeloid differentiation primary response gene 88 MyD88 -independent, suggesting a mechanism unique from that of LPS.


After euthanasia, peritoneal cavities were washed with 8 ml sterile HBSS injected and retrieved. This page was last modified on 23 Februaryat Immunomodulatory activity of acidic polysaccharides isolated from Tanacetum vulgare L. Interestingly, in models very similar to the peritonitis response we describe, such as an experimental sepsis model [ 48 ] and an E.

Both prophylactic and post-exposure strategies involving innate immune stimulation by adjuvants have been shown to prevent or ameliorate infections [ 4445 ]. Recognition profile of Morus nigra agglutinin Morniga G expressed by monomeric ligands, simple clusters and mammalian polyvalent glycotopes. Comparison of lipopolysaccharides from Bacteroides, Porphyromonas, Prevotella, Campylobacter and Wolinella spp.

Macrophage immunomodulation and therapeutic potential. HeJ mice Figure 5C, D. HeJ mice at least 3 per group. Evidence for involvement of the gamma, delta T cell antigen receptor in cytotoxicity mediated by human alloantigen-specific T cell clones. After 3 hours, neutrophil recruitment into the peritoneum was measured by flow cytometry.

Innate immunity for biodefense: Author manuscript; available in PMC Oct 1.

Antimicrobial and anti-inflammatory properties of Funtumia elastica.

Navigation menu Personal tools Log in Request account. Variability in in vitro macrophage activation by commercially diverse bulk echinacea plant material is predominantly due to bacterial lipoproteins and lipopolysaccharides. Support Center Support Center.

The average was based on expression in treated cells from 3 different calves and fkntumia to their expression after uLPS middle and PBS left treatment. Asthma is considered a T H 2 cell-mediated disease, and treatments that increase T H 1 responses can be effective in alleviating symptoms elasyica 54 ]. Therapeutic treatment with Yam-I provided increased innate protection from mucosal infection with Salmonella enterica serotype Typhimurium ST.


Seven hours post-infection, mice were treated by i. Professional antigen-presentation function by human gamma delta T Cells. A colorimetric method for the determination of sugars. Enzymatic treatments suggested protein- and prenylated phosphate-containing compounds were not required for the bioactivity, and nucleic elastifa could not be detected Supplemental Figure S1.

Bradley Jones, University of Iowa for use in an enterocolitis model of ST infection involving pretreatment with streptomycin [ 33 ]. The gamma delta T-cell bridge: Therapeutic treatment with Yam-I resulted in decreased bacterial counts in feces from mice with Salmonella enterica serotype Typhimurium ST -induced elasticx.

Antimicrobial and anti-inflammatory properties of Funtumia elastica.

Toth GB, Pavia H. The role of microbial contaminants in plant-derived products has been the focus of recent elastca [ 4351 ]. Each resulting fraction was applied to bovine PBMC cultures for 24 hours. Eight hours after infection, mice were treated with varying doses of Yam-I by i.

Dittmer U, Olbrich AR. Representative of at least 3 experiments with different donors. Yam-I obtained from before and after two sequential rounds of PMB treatment was tested in the peritonitis model using C3H: Stapf is rather similar to and often co-occurs with F.