cómo se transporta la glucosa través de la membrana celular? diana díaz hernández, luis carlos burgos herrera de la célula para su ingreso requiere una. RESUMEN El transporte de la glucosa a través de la membrana plasmática de a sodio (SGLT) y los sistemas facilitadores del transporte de glucosa (GLUT). Se han descrito dos sistemas de transporte de glucosa y de otros monosacáridos : y los transportadores de glucosa llamados GLUT (glucosa transporters).
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This page was last edited on 24 Octoberat Braz J Med Biol Res ; Physiol Behav ; Int J Obes ; Cloning and functional expresssion in bacteria of a novel glucose transporter present in liver, intestine, kidney, and B-pancreatic islet cells.
J Cell Biol ; Fructose transporter in human spermatozoa and small intestine is GLUT5. In obesity, the GLUT4 content is not diminished providing that insulin sensitiveness is preserved. In familial renal glycosuria, the participation of SGLT2 and SGLT1 seems to be fundamental, either by loss of transport capacity or by decrease in the transporter affinity.
Effect of the thermogenic agent BRL A.
Transportador de glucosa
Biochem J ; The function of these new glucose transporter isoforms is still not clearly defined at present. Diabetes Care ; Abundant during stationary phase, sporulation and low glucose conditions.
American Journal of Physiology. Is expressed by renal tubular cells, liver cells and pancreatic beta cells. Cloning of a human cDNA with similarity to the sodium-glucose cotransporter. Glucose transporter in insulin sensitive tissues of lean and obese mice. Most members of classes II and III have been identified recently in homology searches of EST databases and the sequence information provided by the various genome projects.
Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane. Services on Demand Journal. A topologia dos transportadores de glicose GLUTs inicialmente proposta por Mueckler e cols 2 para o GLUT 1, e posteriormente confirmada para as outras isoformas 12e pode ser vista na Figura 1. Structure and function of mammalian facultative sugar transporters.
A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. The effect of adipose cell size on the measurement of GLUT 4 in white adipose tissue of obese mice.
Machado UF, Saito M. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.
Wright and Eric Turk. Reduced content and preserved translocation of glucose transporter GLUT 4 in white adipose tissue of obese mice.
Quantification of GLUT4 transporter in insulin-sensitive tissues from pinealectomized rats. Evidence for a family of human glucose transporter-like proteins. Mol Genet ; Phloretin Phlorizin T TA. How to cite this article. Binding of glucose to one site provokes a conformational change associated with transport, and releases glucose to the other side of the membrane. GLUTs are integral membrane proteins that contain 12 membrane-spanning helices with both the amino and carboxyl termini exposed on the cytoplasmic side of the plasma membrane.
Each glucose transporter isoform plays a specific role in glucose metabolism determined by its pattern of tissue expression, substrate specificity, transport kinetics, and regulated expression in different physiological conditions.
Regulation of expression of glucose transporters by glucose: In Saccharomyces cerevisiae glucose transport takes place through facilitated diffusion. In pancreatic beta cells, free flowing glucose is required so that the intracellular environment of these cells can accurately gauge the serum glucose levels.
Vesicular glutamate transporter 1 SLC32A1.
Glucose transporter – Wikipedia
J Clin Invest ; Molecular biology of mammaliam glucose transporters. Membrane Transport and Metabolism. Evidence for cytosolic sugar binding sites in erythrocytes”. Regulation of glucose-transporter function.